![]() ![]() Nevertheless, the terms are sometimes used interchangeably. The term acidemia describes the state of low blood pH, while acidosis is used to describe the processes leading to these states. If not further qualified, it usually refers to acidity of the blood plasma. ![]() Not to be confused with Academia.Īcidosis is a process causing increased acidity in the blood and other body tissues (i.e., an increase in hydrogen ion concentration). Consequently, isocapnic ventilation with increased tidal volumes using apparatus dead space increased oxygen and sevoflurane tensions in arterial blood and preserved cardiac output better than did PEEP."Acidemia" redirects here. Cardiac output decreased significantly less in the DS group compared with the PEEP group (5% and 33%, respectively P <. Oxygen tension and arterial sevoflurane concentration were significantly higher in the DS group (P <. ![]() Thirty patients, with ASA physical status 1 or 2, scheduled for elective open colon surgery were randomly assigned to be ventilated with either PEEP at 10 cm H20 (PEEP, 15 patients) or increased tidal volumes achieved with larger apparatus dead space but with zero end-expiratory pressure (DS group, 15 patients). ![]() In the present study, we hypothesize that isocapnic ventilation with increased tidal volumes increases oxygen and sevoflurane uptake similar to ventilation with PEEP, but with less impact on cardiac output. We have earlier demonstrated that increased tidal volumes with larger apparatus dead space improves oxygenation and sevoflurane uptake. Atelectasis formation can be reduced by positive end-expiratory pressure (PEEP), but resulting increases in intrathoracic pressure could affect circulation. ![]()
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